Center for Research on Health Care - Data Center, Current Projects

Data Center Resources

Other Resources

Multidisciplinary Clinical Research Scholars Program

Institute for Clinical Research Education

Center for Research on Health Care (CRHC) Data Center
Suite 200,
200 Meyran Ave, Pittsburgh, PA 15213-3221
Phone: 412-692-4873
E-mail contact:
dcweb@pitt.edu

Data Center: Examples of Current Projects

Click on the project name to find out more about it.

-                                ACCURAY: Prospective Evaluation of Outcomes of Radiosurgical Treatment of Early Stage Non–Small Cell Lung Cancer 
                            
                        
                        
                        
                            
                                BTB: Treatment of Depression Following Cardiac Bypass Surgery
                            
                        
                        
                        
                            
                                CRISP II: Consortium of Radiologic Imaging Studies of Polycystic Kidney Disease
                            
                        
                        
                        
                            
                                PEPPER: Older Americans Independence Center
                            
                        
                        
                        
                            
                                RELAX: Reduce Limitations of Anxiety
+                        Principal Investigator(s): Arjun Pennathur, MD, Assistant Professor of Surgery: Heart, Lung, and Esophageal Surgery Institute.
                        Sponsor: Accuray, Inc.            
                        Grand Type: 0
                        
                            Purpose:
                            To test the efficacy of CyberKnife, developed by Accuray, Inc. Data are collected from patients before, during, and after surgery across 5 sites over 2 years.
                                
                            
                        Data Center Role: Create a Web-based SYSDM that includes tracking, site monitoring, report generation, and data file extraction.
                        Link(s):
                        
                            
                        
                        
                    
                    
                    
                        Principal Investigator(s): Bruce Rollman, MD, MPH.
                        Sponsor: National Heart, Lung, and Blood Institute (NHLBI).            
                        Grand Type: 0
                        
                            Purpose:
                            Depression is common in patients who have undergone coronary artery bypass graft (CABG) surgery and is associated with reduced health-related quality of life (HRQoL) and increased cardiovascular morbidity and mortality. The Bypassing the Blues (BTB) Study offers a novel approach to improving outcomes and potentially reducing health care costs by providing evidence-based treatment for post-CABG depression in the primary care setting.
                                 For more details, click here.
                            
                        Data Center Role: Developed a SYSDM database management application that includes guided data collection for in-hospital data gathering, tracking, reporting, and intervention using both tablet-based and networked desktop PCs.
                        Link(s):
                        
                            
                                    
                                        bypassingtheblues.pitt.edu/
                                    
                                
                        
                        
                    
                    
                    
                        Principal Investigator(s): Vicente Torres, Mayo Clinic; Lisa Guay-Woodford, University of Alabama at Birmingham; Arlene Chapman, Emory University; Jared Grantham, University of Kansas Medical Center; and K. Ty Bae, University of Pittsburgh.
                        Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).            
                        Grand Type: 0
                        
                            Purpose:
                            To determine whether imaging techniques can provide accurate and reproducible markers of progression of renal disease in patients with polycystic kidney disease.  Specifically, the study seeks to draw unequivocal linkage between the rate of kidney cyst enlargement, qualitative endpoints (signs and symptoms), and quantitative endpoints (declining renal function reflected in iothalamate clearance and albuminuria) and to provide a marker of disease progression (kidney volume) that is sensitive and accurate enough to be used as a primary outcome marker in trials aiming to slow disease progression.
                                
                            
                        Data Center Role: Perform the role of data coordinating center for the second 5 years of the CRISP study (CRISP II).  This includes development of a Web-based SYSDM that facilitates data entry, tracking, reporting, and the provision of analytical and statistical support.
                        Link(s):
                        
                            
                                    
                                        Cyst number but not the rate of cystic growth is associated with the mutated gene in autosomal dominant polycystic kidney disease.
                                    
                                
                                    
                                        Renal structure in early autosomal-dominant polycystic kidney disease (ADPKD): the Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) cohort.
                                    
                                
                                    
                                        Volume progression in polycystic kidney disease.
                                    
                                
                        
                        
                    
                    
                    
                        Principal Investigator(s): Stephanie A. Studenski, MD, MPH.
                        Sponsor: National Institute on Aging (NIA).            
                        Grand Type: 0
                        
                            Purpose:
                            The Claude D. Pepper Older Americans Independence Center supports a multidisciplinary effort to understand the causes and consequences of balance disorders in older persons. It integrates 11 independently funded studies, and it includes faculty from 5 schools: medicine, nursing, public health, allied health, and engineering. 
                                
                            
                        Data Center Role: As part of the Data Management and Analysis Core, the Data Center oversees and coordinates database development and data management for all Pepper projects. The Data Center plays a critical role in guiding junior investigators in the development and completion of pilot studies. It has developed a bank of standard instruments that can be used as needed for Pepper studies. It has also developed and maintains the Web-based Pepper Registry, a pool of potential study participants who have consented to be contacted for Pepper research studies.
                        Link(s):
                        
                            
                                    
                                        Striatal dopamine denervation and sensory integration for balance in middle-aged and older adults.
                                    
                                
                                    
                                        Too much or too little step width variability is associated with a fall history in older persons who walk at or near normal gait speed.
                                    
                                
                        
                        
                    
                    
                    
                        Principal Investigator(s): Bruce L. Rollman, MD, MPH.
                        Sponsor: National Institute of Mental Health (NIMH).            
                        Grand Type: 0
                        
                            Purpose:
                            To optimize treatment and 12-month clinical outcomes for primary care patients who have panic disorder, generalized anxiety disorder, or both (PD/GAD).
                                 For more details, click here.
                            
                        Data Center Role: Develop a SYSDM research application that includes guided data collection, tracking, reporting, and intervention using both tablet-based and networked desktop PCs.
                        Link(s):
-Principal Investigator(s):
+Arjun Pennathur, MD, Assistant Professor of Surgery: Heart, Lung, and Esophageal Surgery Institute.
-Sponsor:
+Accuray, Inc.
 Grand Type:
-Purpose:
+To test the efficacy of CyberKnife, developed by Accuray, Inc. Data are collected from patients before, during, and after surgery across 5 sites over 2 years.
-Data Center Role:
+Create a Web-based SYSDM that includes tracking, site monitoring, report generation, and data file extraction.
 Link(s):
-Principal Investigator(s):
+Bruce Rollman, MD, MPH.
-Sponsor:
+National Heart, Lung, and Blood Institute (NHLBI).
 Grand Type:
-Purpose:
+Depression is common in patients who have undergone coronary artery bypass graft (CABG) surgery and is associated with reduced health-related quality of life (HRQoL) and increased cardiovascular morbidity and mortality. The Bypassing the Blues (BTB) Study offers a novel approach to improving outcomes and potentially reducing health care costs by providing evidence-based treatment for post-CABG depression in the primary care setting.
                                 For more details, click here.
-Data Center Role:
+Developed a SYSDM database management application that includes guided data collection for in-hospital data gathering, tracking, reporting, and intervention using both tablet-based and networked desktop PCs.
-Link(s):
+                                        bypassingtheblues.pitt.edu/
-Principal Investigator(s):
+Vicente Torres, Mayo Clinic; Lisa Guay-Woodford, University of Alabama at Birmingham; Arlene Chapman, Emory University; Jared Grantham, University of Kansas Medical Center; and K. Ty Bae, University of Pittsburgh.
-Sponsor:
+National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
 Grand Type:
-Purpose:
+To determine whether imaging techniques can provide accurate and reproducible markers of progression of renal disease in patients with polycystic kidney disease.  Specifically, the study seeks to draw unequivocal linkage between the rate of kidney cyst enlargement, qualitative endpoints (signs and symptoms), and quantitative endpoints (declining renal function reflected in iothalamate clearance and albuminuria) and to provide a marker of disease progression (kidney volume) that is sensitive and accurate enough to be used as a primary outcome marker in trials aiming to slow disease progression.
-Data Center Role:
+Perform the role of data coordinating center for the second 5 years of the CRISP study (CRISP II).  This includes development of a Web-based SYSDM that facilitates data entry, tracking, reporting, and the provision of analytical and statistical support.
-Link(s):
+                                        Cyst number but not the rate of cystic growth is associated with the mutated gene in autosomal dominant polycystic kidney disease.
                                    
                                
                                    
                                        Renal structure in early autosomal-dominant polycystic kidney disease (ADPKD): the Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) cohort.
                                    
                                
                                    
                                        Volume progression in polycystic kidney disease.
-Principal Investigator(s):
+Stephanie A. Studenski, MD, MPH.
-Sponsor:
+National Institute on Aging (NIA).
 Grand Type:
-Purpose:
+The Claude D. Pepper Older Americans Independence Center supports a multidisciplinary effort to understand the causes and consequences of balance disorders in older persons. It integrates 11 independently funded studies, and it includes faculty from 5 schools: medicine, nursing, public health, allied health, and engineering.
-Data Center Role:
+As part of the Data Management and Analysis Core, the Data Center oversees and coordinates database development and data management for all Pepper projects. The Data Center plays a critical role in guiding junior investigators in the development and completion of pilot studies. It has developed a bank of standard instruments that can be used as needed for Pepper studies. It has also developed and maintains the Web-based Pepper Registry, a pool of potential study participants who have consented to be contacted for Pepper research studies.
-Link(s):
+                                        Striatal dopamine denervation and sensory integration for balance in middle-aged and older adults.
                                    
                                
                                    
                                        Too much or too little step width variability is associated with a fall history in older persons who walk at or near normal gait speed.
-Principal Investigator(s):
+Bruce L. Rollman, MD, MPH.
-Sponsor:
+National Institute of Mental Health (NIMH).
 Grand Type:
-Purpose:
+To optimize treatment and 12-month clinical outcomes for primary care patients who have panic disorder, generalized anxiety disorder, or both (PD/GAD).
                                 For more details, click here.
-Data Center Role:
+Develop a SYSDM research application that includes guided data collection, tracking, reporting, and intervention using both tablet-based and networked desktop PCs.
 Link(s):

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