Data Center Resources
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RUPHI
Center for Research on Health Care - Data Center
Suite 200,
200 Meyran Ave, Pittsburgh, PA 15213-3221
Phone: 412-692-4873
email contact:
dcweb@pitt.edu

Data Center - Examples of Current Projects

Click on the project name to find out more about it.

Principal Investigator(s):Arjun Pennathur, MD
Assistant Professor of Surgery
Heart, Lung and Esophageal Surgery Institute
Sponsor:Accuray Inc.
Grand Type:0
Purpose: To test the efficacy of CyberKnife, developed by Accuray Inc. Data are collected from patients before, during, and after surgery across 5 sites over two years.
Data Center Role:Create a web-based SYSDM which includes tracking, site monitoring, report generation, and data file extraction.
Link(s):
Principal Investigator(s):Bruce Rollman, MD, MPH
Sponsor:National Heart Lung and Blood Institute (NHLBI)
Grand Type:0
Purpose: Depression is common in patients who have undergone coronary artery bypass graft (CABG) surgery and is associated with reduced health-related quality of life (HRQoL) and increased cardiovascular morbidity and mortality. The Bypassing the Blues Study offers a novel approach to improving outcomes and potentially reducing healthcare costs by providing evidence-based treatment for post-CABG depression in the primary care setting.
(More details)
Data Center Role:Developed a SYSDM database management application which includes guided data collection for in-hospital data collection, tracking, reporting, and intervention using both tablet-based and networked desktop PCs.
Link(s):
Principal Investigator(s):Vicente Torres, Mayo Clinic
Lisa Guay-Woodford, University of Alabama at Birmingham
Arlene Chapman, Emory University
Jared Grantham, University of Kansas Medical Center
K Ty Bae, University of Pittsburgh
Sponsor:National Institute of Health’s National Institute of Digestive & Diabetes & Kidney Disease
Grand Type:0
Purpose: To determine whether imaging techniques can provide accurate and reproducible markers of progression of renal disease in patients with polycystic kidney disease. Specifically, the study seeks to draw unequivocal linkage between the rate of kidney cyst enlargement and qualitative (signs and symptoms) and quantitative (declining renal function reflected in iothalamate clearance and albuminiuria) endpoints and to provide a marker of disease progression (kidney volume) sensitive and accurate enough to be used as a primary outcome marker in trials aiming to slow disease progression.
Data Center Role:Perform the role of Data Coordinating Center for the second five years of the CRISP study (CRISP II). This includes development of a web-based SYSDM that facilitates data entry, tracking and reporting, and providing analytical and statistical support.
Link(s):

Cyst number, but not the rate of cystic growth, is associated with the mutated gene in ADPKD.

Renal Structure in Early Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) Cohort.

Volume Evolution: A New Concept for Monitoring Disease Progr4ession in Autosomal Dominant Polycystic Kidney Disease.

Principal Investigator(s):Stephanie A. Studenski, MD, MPH
Sponsor:National Institute on Aging
Grand Type:0
Purpose: The Claude D. Pepper Older Americans Independence Center supports a multidisciplinary effort to understand the causes and consequences of balance disorders in older persons. It integrates 11 independently funded studies, and includes faculty from 5 schools: medicine, nursing, public health, allied health, and engineering.
Data Center Role:

As part of the Data Management and Analysis Core, the Data Center oversees and coordinates database development and data management for all Pepper projects. The Data Center

  • plays a critical role in guiding junior investigators in the development and completion of pilot studies
  • has developed a bank of standard instruments that can be used as needed for Pepper studies
  • has developed and maintains the web-based 'Pepper Registry', a pool of potential study participants who have consented to be contacted for Pepper research studies
Link(s):

Striatal dopamine denervation and sensory integration for balance in middle-aged and older adults.

Too much or too little step width variability is associated with a fall history in older persons who walk at or near normal gait speed.

Principal Investigator(s):Bruce L. Rollman, MD, MPH
Sponsor:National Institute of Mental Health (NIMH)
Grand Type:0
Purpose: To optimize treatment and 12-month clinical outcomes for primary care patients with Panic Disorder and/or Generalized Anxiety Disorder (PD/GAD).
(More details)
Data Center Role:Develop a SYSDM research application which includes guided data collection, tracking, reporting, and intervention using both tablet-based and networked desktop PCs.
Link(s):
Principal Investigator(s):Stephen J. O'Keefe
Sponsor:National Institute of Health’s National Institute of Digestive & Diabetes & Kidney Disease
Grand Type:0
Purpose: The Study on Nutrition and Acute Pancreatitis (SNAP) is a 5 year multi-center study in which the University of Pittsburgh is the primary site and 8 other sites across the country would be the secondary sites. Stephen O’Keefe, MD, MSc, FACG from the Division of Gastroenterology, Hepatology and Nutrition is the primary investigator. He is joined by 8 other experts in GI Nutrition as co-investigators. Together, they propose to determine whether distal jejunal (DJ) feeding is more effective than naso-gastric (NG) feeding in providing enteral nutrition to patients with severe acute pancreatitis. Their hypothesis is that DJ feeding is more effective than NG feeding in delivering nutrition to patients with severe acute pancreatitis and better supports the resolution of disease. In order to best facilitate the collection of the extensive daily data that will be needed from so many sites, Dr. O’Keefe has enlisted the assistance of the University of Pittsburgh Data Center. The data from all the sites will be entered daily onto electronic tablets that have been specifically programmed for the study. As the amount of data is so extensive and vital, this capability will be invaluable to the outcome and success of the study as well making the process much more efficient.
Data Center Role:Perform the role of Data Coordinating Center.. This includes development of a tablet-based SYSDM that facilitates data entry, tracking and reporting, and providing analytical and statistical support.
Link(s):

Nutrition support in severe acute pancreatitis.

Nutritional immunomodulation of acute pancreatitis.

Total enteral nutrition or total parenteral nutrition for prophylaxis of infection in patients with severe acute pancreatitis?

Please note: links to journal articles should work when accessing this site from within the UPMC / Pitt network, but may generate errors when accessed externally.

 
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